精神分裂症患者眼底血管变化的研究进展

俞佳琦, 魏燕燕, 张天宏, 王继军

神经病学与神经康复学杂志 ›› 2025, Vol. 21 ›› Issue (3) : 232-237.

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神经病学与神经康复学杂志 ›› 2025, Vol. 21 ›› Issue (3) : 232-237. DOI: 10.12022/jnnr.2025-0155
综述

精神分裂症患者眼底血管变化的研究进展

  • 俞佳琦1,2,魏燕燕1,张天宏1,王继军1
作者信息 +

Research progress on retinal vascular changes in patients with schizophrenia

  • YU Jiaqi1,2, WEI Yanyan1, ZHANG Tianhong1, WANG Jijun1
Author information +
文章历史 +

摘要

精神分裂症是一种严重的精神疾病,其患者相较于普通人群平均寿命缩短10~15年, 主要死亡原因包括心血管疾病、自杀和意外伤害。眼底摄影作为一种无创性检查手段,能 够有效评估微血管病变情况,进而预测心血管疾病的发生风险。鉴于心血管疾病是精神分 裂症患者常见的共病之一,且与患者的高死亡率密切相关,眼底摄影在精神分裂症患者中 的应用,不仅有助于早期识别潜在的心血管问题,还能为预测患者的预期寿命提供重要参 考依据。因此,无创性眼底摄影有望优化精神分裂症患者的监测手段和治疗策略,进而延 长患者寿命。

Abstract

Schizophrenia is a severe mental illness, with patients exhibiting an average lifespan reduction of 10-15 years compared to the general population. The main causes of death in schizophrenia patients include cardiovascular disease, suicide, and accidental injury. As a non-invasive examination method, fundus photography can effectively assess microvascular lesions, thereby predicting the risk of cardiovascular disease. Given that cardiovascular disease is a common comorbidity in schizophrenia patients and is closely related to their high mortality rate, the application of fundus photography in schizophrenia patients not only facilitates early identification of potential cardiovascular problems, but also provides important reference for predicting the patient's life expectancy. Consequently, non-invasive fundus photography holds promise for enhancing monitoring approaches and treatment strategies for schizophrenia patients, ultimately contributing to extended lifespan.

关键词

精神分裂症 / 精神障碍 / 眼底摄影 / 微血管病变 / 视网膜血管

Key words

Schizophrenia / Mental disorder / Fundus photography / Microvascular disease / Retinal vessel

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导出引用
俞佳琦, 魏燕燕, 张天宏, 王继军. 精神分裂症患者眼底血管变化的研究进展[J]. 神经病学与神经康复学杂志. 2025, 21(3): 232-237 https://doi.org/10.12022/jnnr.2025-0155
YU Jiaqi , WEI Yanyan, ZHANG Tianhong , WANG Jijun. Research progress on retinal vascular changes in patients with schizophrenia[J]. Journal of Neurology and Neurorehabilitation. 2025, 21(3): 232-237 https://doi.org/10.12022/jnnr.2025-0155

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