目的：探讨高压氧同步舱内脑电仿生电刺激对脑梗死恢复期患者功能障碍的疗效。

方法：2016 年8 月1 日—2017 年10 月30 日在上海市第八人民医院康复医学科接受康复治疗的68 例脑梗死恢复期患者符合病例选择标准。将68 例患者随机分入研究组（34 例，高压氧同步舱内脑电仿生电刺激治疗）和对照组（34 例，高压氧非同步脑电仿生电刺激治疗）。分别于治疗前、治疗20 d 时、治疗结束后1 个月时、治疗结束后3 个月时应用美国国立卫生研究院卒中量表（National Institute of Health Stroke Scale，NIHSS）评分和改良Barthel 指数评价2 组患者的神经功能缺损程度和日常生活活动能力，并比较治疗20 d 时、治疗结束后1 个月时、治疗结束后3 个月时2 组的临床有效率。

结果：研究组33 例以及对照组31 例患者最终被纳入统计分析。治疗前，2 组的NIHSS评分和改良Barthel 指数差异均无统计学意义（P ＞ 0.05）。治疗20 d 时、治疗结束后1个月时和治疗结束后3 个月时，2 组的NIHSS 评分均较治疗前显著降低（P ＜ 0.05），改良Barthel 指数均较治疗前显著增加（P ＜ 0.05）；研究组的NIHSS 评分均显著低于对照组（P ＜ 0.05），改良Barthel 指数均显著高于对照组（P ＜ 0.05）。研究组的临床有效率亦显著高于对照组（P ＜ 0.05）。

结论：高压氧同步舱内脑电仿生电刺激和高压氧非同步脑电仿生电刺激治疗均可改善脑梗死恢复期患者的功能障碍，尤以高压氧同步舱内脑电仿生电刺激治疗效果更为显著。

Objective: To explore the effect of bionic electrical stimulation synchronized with intrachamber hyperbaric oxygen on patients with cerebral infarction in convalescent period.

Methods: From August 1, 2016 to October 30, 2017, 68 patients with cerebral infarction in convalescent period who received rehabilitation treatment in the Department of Rehabilitation Medicine of Shanghai Eighth People’s Hospital met the criteria for case selection. These 68 patients were randomly divided into study group (34 cases) and control group (34 cases) treated with hyperbaric oxygen synchronized with intrachamber bionic electrical stimulation and hyperbaric oxygen combined with bionic electrical stimulation nonsynchronously, respectively. Neurological impairment and activity of daily living were assessed by the National Institute of Health Stroke Scale (NIHSS) and modified Barthel index before treatment, 20 days after the start of treatment, and 1 month and 3 months after the end of treatment. The clinical effective rates of the 2 groups were evaluated 20 days after the start of treatment and 1 month and 3 months after the end of treatment.

Results: Thirty-three patients in the study group and 31 patients in the control group were included in the final statistical analysis. Before treatment, there was no significant difference in the NIHSS score and the modified Barthel index between the 2 groups (P > 0.05). At 20 days after the start of treatment and 1 month and 3 months after the end of treatment, the NIHSS scores of the two groups were significantly lower and the modified Barthel index were significantly higher than those before treatment (P < 0.05); the NIHSS scores of the study group were significantly lower than those of the control group (P < 0.05), and the modified Barthel index were significantly higher than those of the control group (P < 0.05); the clinical effective rate of the study group was also significantly higher than that of the control group (P < 0.05).

Conclusion: Hyperbaric oxygen synchronized with intrachamber bionic electrical stimulation and hyperbaric oxygen combined with bionic electrical stimulation nonsynchronously can both improve the functional impairment of the patients with cerebral infarction in convalescent period, especially hyperbaric oxygen synchronized with intracabin bionic electrical stimulation is more effective.