伴癫痫持续状态、运动障碍和低通气综合征的自身免疫性脑炎：1例报告及文献复习

王勤鹰; 顾　勤; 余　敏; 姜嘟嘟; 詹　青

doi:10.12022/jnnr.2017-0021

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神经病学与神经康复学杂志 ›› 2017, Vol. 13 ›› Issue (2) : 98-103. DOI: 10.12022/jnnr.2017-0021

病例报告

伴癫痫持续状态、运动障碍和低通气综合征的自身免疫性脑炎：1例报告及文献复习

王勤鹰1, 2，顾　勤1, 2，余　敏1, 2，姜嘟嘟1, 2，詹　青

作者信息 +

Autoimmune encephalitis accompanied with status epilepticus, dyskinesia and hypoventilation syndrome: A case report and literature review

WANG Qinying1, 2, GU Qin1, 2, YU Min1, 2, JIANG Dudu1, 2, ZHAN Qing1, 2

Author information +

文章历史 +

摘要

目的：总结自身免疫性脑炎的临床特征，以减少临床误诊。方法：回顾性分析1例年轻的女性自身免疫性脑炎患者的诊疗过程及随访资料。结果：该患者以发热起病，病情迅速进展，并伴有癫痫持续状态、运动障碍和低通气综合征。诊断为自身免疫性脑炎后，给予免疫治疗。病程3个月时，病情逐渐趋于稳定，并渐趋好转；病程15个月时进行随访，预后较好。结论：临床上对于出现精神障碍、肌张力运动障碍和癫痫的年轻患者，应及时进行自身免疫性脑炎的血清抗体检测和脑脊液检查，以明确诊断。

Abstract

Objective: To summarize the clinical features of autoimmune encephalitis so as to reduce the clinical misdiagnosis. Methods: The diagnosis and treatment and the follow-up data of a young female patient with autoimmune encephalitis were reviewed retrospectively. Results: The patient had a fever as the initial symtom and the disease progressed rapidly with status epilepsy, motor disorders and hypoventilation syndrome. Immunotherapy was administered when the diagnosis of autoimmune encephalitis was confirmed. At the third month since the onset of the disease, the condition of the patient was gradually improved; at the fifteenth month, the patient achieved good prognosis. Conclusion: In clinical practice, a young patient with mental disorders, dyskinesia and epilepsy suspected of autoimmune encephalitis should receive detection of serum antibodies associated with autoimmune encephalitis and the cerebrospinal fluid test to make a definite diagnosis.

导出引用

王勤鹰，顾　勤，余　敏，姜嘟嘟，詹　青. 伴癫痫持续状态、运动障碍和低通气综合征的自身免疫性脑炎：1例报告及文献复习[J]. 神经病学与神经康复学杂志. 2017, 13(2): 98-103 https://doi.org/10.12022/jnnr.2017-0021

WANG Qinying, GU Qin, YU Min, JIANG Dudu, ZHAN Qing. Autoimmune encephalitis accompanied with status epilepticus, dyskinesia and hypoventilation syndrome: A case report and literature review[J]. Journal of Neurology and Neurorehabilitation. 2017, 13(2): 98-103 https://doi.org/10.12022/jnnr.2017-0021

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