目的 探讨加味温胆汤联合利多卡因的中西医结合疗法治疗Lermoyez综合征的临床疗效。方法 20例Lermoyez综合征患者接受利多卡因静脉注射治疗3 d以及加味温胆汤口服治疗2周,随后进行4周的随访。对治疗后的眩晕、耳鸣、耳闷胀感和听力改善情况进行评价。结果 听力显著好转3例（15%）,有效9例（45%）,无效8例（40%）。16例（80%）患者的耳闷胀感减轻（好转）,4例（20%）无变化。17例（85%）患者的耳鸣减轻（好转）,3例（15%）无变化。眩晕治疗有效率为100%,其中65%（13/20）的患者达痊愈,35%（7/20）的患者的眩晕基本得到控制。结论 加味温胆汤联合利多卡因治疗Lermoyez综合征显示出较好的疗效,为今后进一步开展中西医结合治疗提供了临床依据。
Abstract
Objective: To explore the effectiveness of modified Wendan Decoction combined with lidocaine in integrative medical treatment of Lermoyez syndrome. Methods: Twenty patients with Lermoyez's syndrome received intravenous injection with lidocaine for 3 days and oral modified Wendan Decoction for 2 weeks. Before treatment and after 4-week follow-up, the severities of vertigo, low-tone hearing loss, tinnitus and the sensation of ear fullness were evaluated. Results: Of 20 patients, the low-tone hearing was obviously improved in 3 (15%) patients, moderately improved in 9 (45%) patients, and not improved in 8 (40%) patients. The sensation of ear fullness and tinnitus were relieved in 16 (80%) and 17 (85%) patients, respectively, and not relieved in 4 (20%) and 3 (15%) patients. The overall disease control rate of vertigo was 100% including 65% (13/20) achieving full control and 35% (7/20) achieving almost control. Conclusion: The integrative medical treatment with modified Wendan Decoction combined with lidocaine for Lermoyez syndrome can get good efficacy, which provides clinical evidence for further investigation of potential therapeutic methods for this disease.
关键词
Lermoyez综合征 /
加味温胆汤 /
利多卡因
Key words
Lermoyez syndrome /
Modified Wendan Decoction /
Lidocaine
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基金
上海市中西医结合科研专项计划资助项目（编号：2009ZXY003）; 上海市中西医结合治疗脑梗死重点病种建设项目（编号：zxbz2012-20）; 上海市浦东新区名中医及名中医工作室计划资助项目（编号：PDZYXK-3-2014008）; 上海市浦东新区中医神经内科特色专科计划资助项目（编号：PDZYXK-1-2014004）; 上海市浦东新区名中医继承人培养建设项目（编号：PDZYXK-6-2014038,PDZYXK-6-2014019）
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