帕金森病(Parkinson's disease,PD)是继阿尔茨海默病之后的第2大神经退行性疾病其定义为一种由黑质进行性神经元丧失引起的复杂的进行性神经退行性疾病，常见的临床表现包括震颤、强直、运动迟缓和姿势不平衡,还常伴有便秘、睡眠行为异常和抑郁等非运动症状以及糖尿病、冠心病和骨质疏松等多种共病。循环系统疾病为 PD 最常见的共病,包括心血管自主神经功能异常、心肌病、冠心病、心律失常、心源性猝死和 PD 猝死等,其中最常见的是心血管自主神经功能异常。本文对PD与循环系统共病的进展进行综述。

Parkinson's diseasePD)is the second most common neurodegenerative disorder after Alzheimer's disease and it is defned as a complex progressive neurodegenerative disorder referred by tremor, rigidity, bradykinesia, and postural imbalance because of progressive neuronal loss in the substantia nigra. PD usually accompanies with a numbel of non-motor symptoms, such as constipation, sleep disorder, depression, and also some other comorbidities, such as diabetes, coronary heart disease, osteoporosis. Circulatory system diseases are the most common comorbidities of PD. Circulatory system comorbidities of PD incude cardiac autonomic dysfunction, cardiomyopathy, coronary heart disease arrhythmias, sudden cardiac death (SCD), and sudden unexpected death in PD (SUDPAR).The most prominent circulatory system comorbidity is cardiac autonomic dysfunction. This review will analyze and discuss the circulatory system comorbidities of PD.