主动脉粥样硬化合并动脉瘤致横贯性脊髓梗死:1例报告及专家解读

万文斌1,郝 勇1,徐 群1,陈 莺1,陈增爱2,管阳太1

神经病学与神经康复学杂志 ›› 2018, Vol. 14 ›› Issue (2) : 93-99.

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神经病学与神经康复学杂志 ›› 2018, Vol. 14 ›› Issue (2) : 93-99. DOI: 10.12022/jnnr.2018-0053
神经影像专家解读

主动脉粥样硬化合并动脉瘤致横贯性脊髓梗死:1例报告及专家解读

  • 万文斌1,郝 勇1,徐 群1,陈 莺1,陈增爱2,管阳太1
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Transverse spinal cord infarction induced by aortic atherosclerosis combining with aneurysm: one case report and specialist interpretation

  • WAN Wenbin1, HAO Yong1, XU Qun1, CHEN Ying1, CHEN Zengai2, GUAN Yangtai1
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摘要


目的:探讨主动脉粥样硬化合并动脉瘤致横贯性脊髓梗死的临床表现和影像学特征,以期提高对本病的认识。

方法:报道1 例主动脉粥样硬化合并动脉瘤致横贯性脊髓梗死患者的临床诊治经过,邀请神经内科及影像科专家结合相关文献对本病的临床表现及影像学特点进行解读。

结果:1 例主动脉粥样硬化合并动脉瘤致横贯性脊髓梗死患者的临床表现为反复双下肢麻木、无力后出现病情进行性加重。脊髓磁共振成像(magnetic resonance imaging,MRI)显示下胸段脊髓及腰髓略肿胀伴信号异常;计算机断层成像血管造影(computed tomography angiography,CTA)显示主动脉弓外壁瘤样扩张伴粥样硬化,内壁多发溃疡伴附壁血栓;双侧颈动脉分叉部及颈内动脉起始端粥样斑块伴管腔狭窄;左侧髂总动脉局段夹层改变,左侧髂内动脉局部附壁血栓形成伴管腔明显狭窄。明确诊断后,将患者转至血管外科行主动脉瘤介入治疗。

结论:脊髓梗死发病率远低于脑梗死,而主动脉疾病是导致脊髓梗死的常见原因。急性起病以及病情迅速发展达到高峰是脊髓梗死的特点,通过结合脑脊液及MRI 检查,大多数病例可以得到明确诊断,然而其病因仍有赖于通过CTA 和数字减影血管造影(digital substraction angiography,DSA)检查等予以明确。本病缺乏特效的治疗手段,目前仅有少数针对病因的治疗方法。

Abstract


Objective:
To investigate the clinical and imaging characteristics of transverse spinal cord infarction (SCI) induced by aortic atherosclerosis combined with aneurysm, so as to improve the understanding of the disease in clinical practice.

Methods: One case of transverse SCI induced by aortic atherosclerosis combined with aneurysm and its clinical diagnosis and treatment process were reported. Neurological and imaging specialists were invited to discuss the clinical manifestations and imaging features of the disease based on the relevant literature review. 

Results: The clinical manifestations of a case of transverse SCI induced by aortic atherosclerosis combined with aneurysm were repeated numbness and weakness of the lower extremities with progressive aggravation. Magnetic resonance imaging (MRI) revealed an abnormal signal and slight swelling of the lower thoracic and lumbar spinal cord. Computed tomography angiography (CTA) showed dilated outer wall of the aortic arch, aortic atherosclerosis of aorta, and multiple ulcers in the inner wall of the aortic arch with mural thrombus; atherosclerotic plaques at both sides of the carotid bifurcation and the origin of the internal carotid artery with the stenosis of vascular cavity; dissecting changes in left common iliac artery, and localized mural thrombus in left internal iliac artery with obvious stenosis of vascular cavity. After definitive diagnosis, this case was transferred to interventional surgery for aortic aneurysm.

Conclusion: The incidence rate of SCI is much lower than that of cerebral infarction. Aortic disease is one of the common causes of SCI. Acute onset and rapid progression to its peak are the characteristics of SCI. By combining cerebrospinal fluid and MRI examinations, most patients can be definitely diagnosed. However, its etiology still depends on CTA and digital substraction angiography (DSA) examination. There is no effective treatment for SCI. At present, only a few treatment methods have been proposed for etiology.

关键词

脊髓梗死 / 主动脉 / 动脉粥样硬化 / 动脉瘤 / 影像学

Key words

Spinal cord infarction /  Aorta /  Atherosclerosis /  Arterial aneurysm /  Imaging

引用本文

导出引用
万文斌1,郝 勇1,徐 群1,陈 莺1,陈增爱2,管阳太1. 主动脉粥样硬化合并动脉瘤致横贯性脊髓梗死:1例报告及专家解读[J]. 神经病学与神经康复学杂志. 2018, 14(2): 93-99 https://doi.org/10.12022/jnnr.2018-0053
WAN Wenbin1, HAO Yong1, XU Qun1, CHEN Ying1, CHEN Zengai2, GUAN Yangtai1. Transverse spinal cord infarction induced by aortic atherosclerosis combining with aneurysm: one case report and specialist interpretation[J]. Journal of Neurology and Neurorehabilitation. 2018, 14(2): 93-99 https://doi.org/10.12022/jnnr.2018-0053

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