Objective: To explore the effect of Taijiquan exercise on motor and balance function of patients with Parkinson's disease (PD).

Methods: To search the randomized controlled trials of the efficacy of Taijiquan exercise in patients with PD from 7 Chinese and English databases. The search time is from the database establishment date to January 31, 2022. According to the Cochrane Handbook 5.1.0 standard,two researchers independently evaluated the quality and bias risk of each included literature, and extracted data. Meta analysis was conducted using RevMan 5.4.1 software.

Results: A total of 12 randomized controlled trials (RCTs) were included, involving 585 patients. The Meta analysis results showed that Taijiquan exercise can significantly reduce the Unified PD Rating Scale Part III (UPDRS III) scores mean difference:-3.09 (95% confidence interval:-4.54 to-1.64); P<0.0001] and Timed Up and Go Test (TUG) scores[mean difference:-1.33 (95% confidence interval: -1.83 to-0.84); P<0.000 01, increased the Berg Balance Scale scores [mean difference: 6.73 (95% confidence interval: 6.55 to 6.90);P<0.000 01. However, there was no significant impact on the 6-minute Walk Test (6-MWT) scores [mean difference: 4.54 (95% confidence interval: -10.63 to 19.72); P=0.56].

Conclusion: Taijiquan exercise can improve the motion and balance abilities of patients with PD, and improve their quality of life. However, there is insufficient evidence for the improvement of walking ability.