Acupuncture and moxibustion for stroke has a significant effect and a wide range of indications, and has an irreplaceable position. The case registration research based on the real world has become an important research method in clinical research because of its authenticity, high reliability and more clinical applicable conclusions. The application of this research method to the clinical research of acupuncture, moxibustion and stroke is a hot research topic at home and abroad. By searching and sorting out the previous patient registry studies on acupuncture, moxibustion and stroke, this paper reviewed the application and research status of related patient registration platforms, and summarized the relevant research results of the China National Stroke Registration (CNSR), to explore the importance of building a patient registration platform of acupuncture and moxibustion for stroke to assist clinical and academic research.