Post-stroke spasm is an important cause of high disability rate after stroke. Spastic paralysis after stroke has become a difficult clinical problem because of its “difficult to identify and treat”. If spasm is not treated promptly and effectively, it will not only cause limb pain, but also lead to muscle atrophy and joint contracture and deformation, which will restrict joint movement, affect the effectiveness of rehabilitation training, and even aggravate the condition. Therefore, effective prevention and treatment of spastic paralysis after stroke is an important measure to improve the quality of life of patients. This paper reviews the possible pathogenesis, evaluation methods and rehabilitation treatment of post-stroke spastic paralysis, in order to provide references for the prevention and treatment of poststroke spastic paralysis.