Objective: To retrospectively analyze the effect of Nao-Xue-Shu Oral Liquid (NXS) on the absorption of intracerebral hematoma in patients with hypertensive intracerebral hemorrhage.

Methods: The medical records of eighty-four patients with hypertensive cerebral hemorrhage were retrospectively collected. The patients were divided into NXS group (n = 41) and basic treatment group (n = 43). Both groups received oxygen inhalation, hemostasis, dehydration, blood pressure control, basic disease treatment and symptomatic and supportive treatment. The patients in the NXS group received NXS orally or by nasal feeding within 72 hours since the disease onset. Both groups were treated for 10 days. Before treatment and 10 days after treatment, the volume of intracerebral hematoma was observed and calculated by computed tomography (CT), and the use of dehydration and antihypertensive drugs during treatment was recorded.

Results: There was no significant difference in gender, systolic blood pressure, diastolic blood pressure and intracerebral hematoma volume between the two groups before treatment (P > 0.05), but there was significant difference in age (P = 0.005). There was no significant difference in the use rate of dehydration and antihypertensive drugs between the two groups during treatment (P = 0.529, P = 0.898); after 10 days of treatment, the volumes of intracerebral hematoma of the two groups were smaller than those before treatment, but only the change of volume of intracerebral hematoma in the NXS group had statistical significance (P = 0.001). The volume of intracerebral hematoma in the NXS group after treatment for 10 d was significantly smaller than that in the basic treatment group (P = 0.046). Multiple linear regression analysis showed that age and blood pressure had no significant correlation with the volume of intracerebral hematoma before and after treatment and the absorption of intracerebral hematoma (P > 0.05).

Conclusion: NXS can reduce the intracerebral hematoma and promote the absorption of intracerebral hematoma in patients with hypertensive cerebral hemorrhage, but has no obvious effect on the use of dehydration and antihypertensive drugs.