Endogenous neural stem cells and ischemic stroke

CHEN Miao; ZHAN Qing

doi:10.12022/jnnr.2016-0044

Journal of Neurology and Neurorehabilitation ›› 2016, Vol. 12 ›› Issue (3) : 157-160. DOI: 10.12022/jnnr.2016-0044

Review

Endogenous neural stem cells and ischemic stroke

CHEN Miao1, ZHAN Qing2, 3

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Abstract

Neural stem cell therapy, as a new therapeutic method for all kinds of nervous system diseases, has aroused wide concern for over 20 years since being first found in 1992. Ischemic stroke is highly concerned because of its high incidence, high mortality and high disability rate. The research advances in functions of endogenous neural stem cells in nerve regeneration and neovascularization and their interactions as well as the related regulators in these two important processes after ischemic stroke are summarized in this review, hoping to provide new ideas of accelerating neural functional recovery after ischemic stroke.

Key words

Brain ischemia / Neural stem cells / Nerve regeneration / Neovascularization, pathologic

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CHEN Miao, ZHAN Qing. Endogenous neural stem cells and ischemic stroke[J]. Journal of Neurology and Neurorehabilitation. 2016, 12(3): 157-160 https://doi.org/10.12022/jnnr.2016-0044

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Funding

Advanced Talents Training Program of Integrated Chinese and Western Medicine, Shanghai Three-year Action to Further Accelerate the Development of Traditional Chinese Medicine (No. ZY3-RCPY-4-2009); Study Program of Early Emergency Management and Process Optimization of Ischemic Stroke (No. 201440496)