Objective: To explore the effectiveness of modified Wendan Decoction combined with lidocaine in integrative medical treatment of Lermoyez syndrome. Methods: Twenty patients with Lermoyez's syndrome received intravenous injection with lidocaine for 3 days and oral modified Wendan Decoction for 2 weeks. Before treatment and after 4-week follow-up, the severities of vertigo, low-tone hearing loss, tinnitus and the sensation of ear fullness were evaluated. Results: Of 20 patients, the low-tone hearing was obviously improved in 3 (15%) patients, moderately improved in 9 (45%) patients, and not improved in 8 (40%) patients. The sensation of ear fullness and tinnitus were relieved in 16 (80%) and 17 (85%) patients, respectively, and not relieved in 4 (20%) and 3 (15%) patients. The overall disease control rate of vertigo was 100% including 65% (13/20) achieving full control and 35% (7/20) achieving almost control. Conclusion: The integrative medical treatment with modified Wendan Decoction combined with lidocaine for Lermoyez syndrome can get good efficacy, which provides clinical evidence for further investigation of potential therapeutic methods for this disease.
Key words
Lermoyez syndrome /
Modified Wendan Decoction /
Lidocaine
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Funding
Special Research Foundation of Shanghai Integrative Medicine (No. 2009ZXY003); Shanghai Integrative Medicine Foundation for Major Disease Stroke (No. zxbz2012-20); Famous Traditional Chinese Medicine Doctor and Famous Traditional Chinese Medicine Consulting Office Foundation of Shanghai Pudong New Area (No. PDZYXK-3-2014008); Project of Characteristic Specialty Neurology of Traditional Chinese Medicine of Shanghai Pudong New Area (No. PDZYXK-1-2014004); Famous Traditional Chinese Medicine Personal Training Foundation of Shanghai Pudong New Area (No. PDZYXK-6-2014038, PDZYXK-6-2014019)
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