Objective: To explore the mechanism of early recovery of motor aphasia after cerebral infarction using regional homogeneity(ReHo) based techniques using resting state functional magnetic resonance imaging.

Methods: Ten patients with motor aphasia after cerebral infarction were selected as the aphasia group, and 10 patients without aphasia during the same period were selected as the control group. All patients underwent resting fMRl examination. Apply SPM8 software and DPARSF software to process the data, and use REST for 2-sample t-test.

Results: Compared with the control group, the aphasia group had higher ReH0  in the left cerebellum (MNl: x=-27,y=-60,2=-18;t=3.33), left occipital lobe (MNl: x=-45, y=-692=15; 5.26) and right middle temporal gyrus (MNl: x=51, y=?51,2=9; t=7.49). The brain areas with lower ReHO in the aphasia group compared to the control group were left medial prefrontal gyrus (MNl: x=-24, y=75, 2=3; t=-3.75), left superior frontal gyrus and left middle frontal gyrus (MNl: x=-36, y=9, z=66;t=-4.44), left angular gyrus (MN: x=-66, y=-60,z=42; t=-2.67), left parietal lobe(MNl: x=-57, y=-84, 2=48; t=-3.23), left upper and lower parietal lobules(MNl: x=-21,y=-42,2=87; t=-3.50), right angular gyrus(MNl: x=-54, y=-84, 2=21; t=-4.00)right supramarginal gyrus (MNl: x=63, y=-69, 2=57; t=-4.16) and right occipital lobe (MN!:x9,y=-105,2=24; t--4.38).

Conclusion: In the acute phase of motor aphasia after cerebral infarction, the activation of the left cerebellum, left occipital lobe, and right temporal lobe is enhanced. These brain regions may participate in early functional compensation and are the recovery mechanism of the acute phase; The activation of left medial prefrontal gyrus, left superior frontal gyrus, left middle frontal gyrus, left superior parietal lobule, inferior parietal lobule and parietal lobe is reduced, which may be the mechanism of motor aphasia after cerebral infarction.